Mapping care pathways for ulcerative colitis patients in North West London

Mapping care pathways for ulcerative colitis patients in North West London

Mapping care pathways for ulcerative colitis patients in North West London image
  • 18th March 2019

St Mark’s Hospital, Bowel & Cancer Research



Ulcerative Colitis (UC) is the most common type of Inflammatory Bowel Disease (IBD). In the UK, the annual incidence of ulcerative colitis is 10 cases per 100,000 individuals, and the prevalence is 240 per 100,000. Research conducted by Crohn’s and Colitis UK shows: patient dissatisfaction with their treatment; variation in service and pathway, and poor access to healthcare professionals.


Research objective

To describe and quantify current real world burden of treating patients with ulcerative colitis from across NHS organisations and settings in North West London.


A retrospective study analysing integrated NHS patient care data from the WISC dataset.

Participants and setting

Eligible patients, including adults over 18 years old with ulcerative colitis with mild, moderate and severe systems.


Firstly to identify the cohort of patients diagnosed with ulcerative colitis and provide a description of demographics of the cohort in terms of age, ethnicity, BMI, and co-diagnosis by disease severity.

Describe the average patient journey in each cohort from symptoms, diagnosis to treatment in terms of stages, timing, type of NHS resources mostly consumed and costs attributed by the North West London whole integrated NHS system. The burden of disease of the population by disease severity will be quantified in terms of costs as well as total number of activities by NHS organization.

A subanalysis on patients treated with biologics will also be conducted to understand the patient journey up to treatment and after in terms of NHS resource utilization according to the sequencing of the treatment chosen for patients resulting from variable effectiveness.

The NWL Health Research Register team provided assistance with with a cohort feasibility search as well as data analysis and interpretation of the NHS Whole Systems Integrated Care (WSIC) dataset.


This study aims to achieve a better understanding of patient pathways and the burden of disease of people suffering from ulcerative colitis. It will also help us gain a better understanding of current standards of care with biologics and lead to future improvements in choice of alternative treatments.

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